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Article URL: https://www.science.org/doi/10.1126/sciadv.adu1598

Comments URL: https://news.ycombinator.com/item?id=43756591

Points: 1

# Comments: 0

Watch The Last of Us, Hacks and more when you pay for a year upfront.

Article URL: https://openreview.net/pdf?id=xoXn62FzD0

Comments URL: https://news.ycombinator.com/item?id=43756352

Points: 1

# Comments: 0

Article URL: https://www.vice.com/en/article/this-bird-went-extinct-and-then-evolved-into-existence-again/

Comments URL: https://news.ycombinator.com/item?id=43756345

Points: 1

# Comments: 0

Article URL: https://theconversation.com/wide-variety-of-old-growth-ecosystems-across-the-us-makes-their-conservation-a-complex-challenge-253004

Comments URL: https://news.ycombinator.com/item?id=43756334

Points: 1

# Comments: 0

Article URL: https://www.epic.com/visiting/

Comments URL: https://news.ycombinator.com/item?id=43756309

Points: 1

# Comments: 0

Article URL: https://www.tomshardware.com/pc-components/nas/synology-requires-self-branded-drives-for-some-consumer-nas-systems-drops-full-functionality-and-support-for-third-party-hdds

Comments URL: https://news.ycombinator.com/item?id=43756305

Points: 1

# Comments: 2

Article URL: https://github.com/marwanhawari/stew

Comments URL: https://news.ycombinator.com/item?id=43756301

Points: 1

# Comments: 0

I'm considering building an open-source alternative to Clay.com (the customer intelligence/data enrichment platform). The core concept would be a self-hostable solution that can:

Enrich contact and company data from public sources Create custom data tables with flexible schemas Automate data maintenance and updating Connect with common CRMs and productivity tools Prioritize privacy and data ownership

My motivation: While Clay offers a great product, I believe data enrichment should be accessible to smaller teams and individuals without enterprise budgets. An open-source alternative would democratize access to these capabilities. Some technical challenges I'm considering:

How to handle API rate limits for various data sources Building a scalable architecture for processing large datasets Ensuring GDPR/CCPA compliance Creating a user-friendly interface comparable to commercial options

If you're interested in contributing or would use this type of tool, I'd love to hear your thoughts. What features would be most valuable? What integrations would you need? Any insights about potential pitfalls or suggestions on how to approach this project? Has anyone attempted something similar already that I could learn from?

Comments URL: https://news.ycombinator.com/item?id=43756298

Points: 1

# Comments: 0

I created a simple app to explore how Agents & MCP can help with medical research. It connects to ClinicalTrials.gov, PubMed/PubTator, and MyVariant.info using the BioMCP Server(https://github.com/genomoncology/biomcp), and uses Haystack(https://github.com/deepset-ai/haystack) as the MCP Client.

The idea is to let users ask natural-language questions like: - Are there new studies on treating acne? - What trials exist for migraine prevention? - Show me trials for managing hay fever symptoms - What are some ongoing trails for never-smokers with lung cancer?

If you’re curious, here are the links: - MedOryx App: https://med-oryx.streamlit.app - MedOryx GitHub: https://github.com/oryx1729/med-oryx

Would love any feedback or thoughts.

Comments URL: https://news.ycombinator.com/item?id=43756257

Points: 1

# Comments: 0

Article URL: https://oban.pro/articles/weaving-stories-with-cascading-workflows

Comments URL: https://news.ycombinator.com/item?id=43756251

Points: 1

# Comments: 0

Article URL: http://bannalia.blogspot.com/2022/11/inside-boostunorderedflatmap.html

Comments URL: https://news.ycombinator.com/item?id=43756245

Points: 1

# Comments: 0

If you use AI Agents in your workflows, where does ownership apply? Is it the human or the agent?

Comments URL: https://news.ycombinator.com/item?id=43756239

Points: 1

# Comments: 1

I built a web app inspired by the bar scene in Inglourious Bastards, where characters guess identities with limited information.

You can try it here: https://xoself.com/guess

Scene that inspired it (starts ~5:40): https://www.youtube.com/watch?v=a6IVkQ8-Lx8

Comments URL: https://news.ycombinator.com/item?id=43756206

Points: 2

# Comments: 1

The agency has reportedly been instructed to turn most of its focus to big banks.

Article URL: https://react.dev/blog/2025/04/21/react-compiler-rc

Comments URL: https://news.ycombinator.com/item?id=43756179

Points: 1

# Comments: 0

Article URL: https://github.com/blues/padlock

Comments URL: https://news.ycombinator.com/item?id=43756178

Points: 3

# Comments: 1

Article URL: https://sizeof.cat/post/web-browser-telemetry-2025-edition/

Comments URL: https://news.ycombinator.com/item?id=43756167

Points: 3

# Comments: 1

Article URL: https://bitskingdom.com/blog/3-basic-questions-about-next-js/

Comments URL: https://news.ycombinator.com/item?id=43756151

Points: 1

# Comments: 0